Which,Herpes,Medicine,More,Eff health Which Herpes Medicine is More Effective - Valacyclovir or Ac
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Valacyclovir (Valtrex, marketed by GlaxoSmithKline) and acyclovir (Zovirax, marketed by Sanofi-Aventis) are used mainly for treatment of genital herpes. Both are antiviral drugs and can be taken orally to shorten herpes symptoms or to prevent this infection from recurring in healthy individuals. Acyclovir pills had been in use from 1991 and enjoying the status of a first-of-its-kind antiviral drug for genital herpes treatment, until Valtrex was approved by the US Food and Drug Administration (FDA) 4 years later in 1995. The valacyclovir vs acyclovir debate started since then and it still remains a matter of research interest as to which drug you can use to cope with herpes better.Valacyclovir advantagesValacyclovir has a number of key advantages over other similar antiviral medications. Clinical trials have shown that this drug has greater effectiveness in dealing with the herpes simplex virus (HSV) or the varicella zoster virus (VZV), compared to acyclovir or other drugs. Another plus factor of Valtrex is that it is probably the only medicine that can reduce the risk of herpes transmission, given that safe sex methods are used. As far as shingles (herpes zoster) treatment is concerned, valacyclovir can lessen the severity of post-zoster pain quicker than acyclovir.The GlaxoSmithKline drug also provides better oral bioavailability than acyclovir. It implies that when you take a pill, your circulatory system will receive most of its ingredients unchanged. It is estimated that valacyclovir provides about 70% bioavailability. The risk of drug interactions is also minimum with valacyclovir, compared to some of the other antiviral herpes medicines.Convenient dosing schedule is one of the major advantages of Valtrex. You can take 500mg Valtrex pills twice a day to reduce the severity of a herpes outbreak. It makes valacyclovir a more convenient option than acyclovir as you need to take the latter drug 5 times a day to get the same kind of results.Acyclovir advantagesAs a pioneering drug for the treatment of genital herpes, herpes zoster and chickenpox, acyclovir has its own unique benefits as well. It has an unmatched safety and tolerance record. also, acyclovir can be very effective in suppressing viral shedding. Like valacyclovir, acyclovir too does not pose any great risk of drug interactions. No major problem have been reported so far in cases of pregnant women taking this drug.Disadvantages of antiviral herpes medicinesBoth valacyclovir and acyclovir can increase the risk of kidney failure and neurotoxicity. Also, neither of them can kill the virus that causes herpes.Which of the two medicines is better?Considering all advantages and disadvantages of these two drugs, it is fair to say that valacyclovir has a slight edge over acyclovir. It is ahead mainly on two points - convenient dosing and high bioavailability. Having said that, a particular medicine that may suit you may not suit another individual. So always seek expert consultation to find out which of these drugs is appropriate for you. Article Tags: Genital Herpes
Which,Herpes,Medicine,More,Eff