What,Leaky,Gut,Syndrome,and,Ho health What Is Leaky Gut Syndrome and How Does It Relate to Treatin
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Leakygut syndrome is a phenomenon in which micro-particles, i.e. foodfragments, viruses, bacteria and yeast proteins, and other bio-toxicmaterial are leeched into the blood stream from a breakdown of theintestinal mucosal barrier. With respect to autism, leaky gut isthought to contribute to unwanted molecules (food, bacteria, yeast,etc.) permeating through the intestinal wall and cross-reacting withthe immune system (leading to increased susceptibility for allergies)and the brain (leading to problems in cognitive function, language,and behavior), as well as leading to brain inflammation. Leakygut syndrome is detrimental for a persons health because toxicsubstances which are normally bound in the fecal matter making itsway through the digestive system for eventual elimination, now hasaccess through a permeable mucosal membrane leading to physicalstress throughout the body. For example, a food protein like gliadin(found in wheat) may trigger brain chemical reactions alteringattention, mood, sleep and pain response. If the substance is from anintestinal pathogen such as a bacteria it can trigger immunereactions leading to autoimmune disorders. Autoimmune is the processof the bodys immune system attacking itself and it is known thatvarious infectious proteins can trigger this response, i.e. bacterialtoxins leading to reactive arthritis (formally called ReitersSyndrome) or PANDAS a autoimmune post-streptococcal infectioncondition triggered by group A beta-hemolytic streptococcus. Whatcauses leaky gut syndrome is not entirely known. In autism, part ofthe issue could be gluten sensitivity. Gluten is a protein found inwheat that certain individuals have a difficult time digesting. Withthe inability to breakdown gluten in the gut an inflammatory reactionis created which weakens the gut wall. Inside the gut wall aremillions of tiny cells that are responsible for absorbing nutrientsfrom our diet, as well as releasing enzymes to help breakdown thefood stuff in the gut. The spaces between cells are vulnerablethrough something called a tight junction. A tight junction ismaterial that holds cells together. Think of it like mortar betweenbricks in a wall. If the mortar breaks down than overtime the brickscollapse and the wall falls over. The same thing can happen in thedigestive system with the tight junctions breaking down and the spacebetween cells becoming more leaky. Otherpotential contributing factors to leaky gut are alcohol, caffeine,certain drugs like ibuprofen and diets high in carbohydrates. Inautism, a diet called the Specific Carbohydrate Diet is used toeliminate the build-up of inflammation in the gut from hard to digestcarbohydrates, i.e. corn, potatoes, rice. The results with this dietcan be remarkable in helping autism-spectrum individuals improvetheir health and overall cognitive abilities. For parents withautistic children, as well as doctors and researchers looking at therole of leaky gut in autism, there is always more to understand withrespects to causes and treatment. Simply understanding that leaky gutexists in autism is important and will help everyone involved in thecare of an autistic individual better understand some of the reasonsbehind their health and cognitive challenges.
What,Leaky,Gut,Syndrome,and,Ho