Colorectal,and,hereditary,non, health Colorectal and hereditary non polyposis colorectal cancer
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Summary: Who IsMore Prone To Develop Colorectal Cancer?Colorectal cancerrepresent over 9 percent of all cancers in men and about 10 percent of allcancers in women world-wide. In industrialized countries the incidence ofcolorectal cancer can be as high as 12 to 14 of all cancers, and innon-industrialized countries much lower rates of about 7 to 8 percent of allcancers diagnosed may be colorectal cancer.Excluding skin cancer,colorectal cancer is the third commonest cancer diagnosed in the United States.Each year over 100,000 Americans are diagnosed with colon cancer and over 50percent of these patients will die from colorectal cancer. Even though we donot know the exact cause of development of colorectal cancer, scientists haverecognized several factors that can increase the risk of development ofcolorectal cancer. The simple presence of one or more risk factors does notnecessarily mean that someone will develop colorectal cancer. On the other handabsence of all risk factors does not mean that an individual will not developcolorectal cancer, but generally more risk factors you have higher is thechance of developing colorectal cancer. Environmental factors also may beplaying a role in the development of colorectal cancer. People who migrate fromareas of low risk to areas of the world with higher risk of developingcolorectal cancer, they tend to acquire the risk of the country to which theyare migrating. This finding suggests the presence of environmental factorscausing higher risk of developing colorectal cancer. Changes in dietary factorsassociated with migration may also be contributing to this increase in riskassociated with migration from low risk areas to higher risk areas.Risk factors for thedevelopment of colorectal cancer include the following: · Age over 50 years· Increased fat intake· Large intestinalpolyps· Family history ofcolon cancer· Inflammatory boweldiseases like ulcerative colitis and Crohn's disease.· Personal history ofother cancers· Sedentary habits andlack of exercise· Obesity· Diabetes· Smoking· Alcohol content· Genetic colon cancersyndromes like Familial adenomatous polyposis or Hereditary Non-polyposis ColonCancer (HNPCC)Persons who have highrisk of colorectal cancer may undergo screening for colorectal cancer withcolonoscopy once every 2 to 3 years.Summary: The Best Way to PreventColorectal CancerMost colorectal canceris considered sporadic, meaning it occurs in people with no family history ofthe disease. In general, both men and women at average risk of colorectalcancer should begin screening tests at age 50.Testing stool samplesfor genetic alterations that occur in colorectal cancer cells may help doctorsfind evidence of cancer or precancerous polyps. In some patients, genetictesting can guide screening and may be cost-effective. Approximately 25% ofcases are attributed to two types of colorectal cancers: familial andhereditary. Familial colorectal cancer accounts for about 20% of cases andhereditary colorectal cancer accounts for the remaining five percent. Youshould discuss beginning earlier screening if you have a personal history ofcolorectal cancer or polyps, a strong family history of either, a personalhistory of chronic inflammatory bowel disease or a family history of ahereditary colorectal cancer syndrome. The Genetic counseling and genetic are testingfor families who may have a hereditary form of colon cancer, such as hereditarynon-polyposis colorectal cancer (HNPCC) or familial adenomatous polyposis(FAP).Since most colonpolyps and early cancers are silent (produce no symptoms), it is important todo screening and surveillance for colon cancer in patients without symptoms orsigns of the polyps or cancers. Although there are good colorectal cancerscreening tests, not enough people have them done. Cancer prevention is actiontaken to lower the chance of getting cancer. Some cancer prevention trials areconducted with healthy people who have not had cancer but who have an increasedrisk for cancer.Preventionof colorectal cancer: Although the exact cause of colorectal cancer is not known, itis possible to prevent many colon cancers with the following: diet andexercise.
Colorectal,and,hereditary,non,