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Intensive control of bloodsugar levels reduces the risk of certain signs of kidney damage amongdiabetics, and decreases the intake of Canadiandrugs to a minimum. However, the evidence did notshow that intensive control lowers the risk of actually developing severekidney disease. "Our analysisdemonstrates that, after 163,828 patient-years of follow-up in the sevenstudies examined, intensive glycemic [blood sugar] control lessensalbuminuria," but there's not enough data to say if that benefit extendsto kidney disease or kidney failure, wrote Dr. Steven Coca, of Yale University,and colleagues. This may mean that there'slittle point to beginning intensive blood-sugar control in the mid-stage of type2 diabetes in an attempt to prevent kidney failure, they concluded. However, an expert notinvolved in the study says the studies included in this meta-analysis were tooshort to assess how intensive blood-sugar control might affect the risk ofkidney failure in patients with type 2 diabetes. "Although implementingintensive therapy is difficult and imposes burden and expense, all of theprimary data continue to support its long-term benefit," Dr. David Nathan,of Massachusetts General Hospital, wrote in an accompanying editorial. "I feel this [finding] ismisleading since most of the studies included in the analysis had relativelyshort durations of 'intensive' treatment and also fairly short durations offollow-up," said Dr. Tracy Breen, director of diabetes care at NorthShore-LIJ Health System in New Hyde Park, N.Y. She added that"microvascular complications often take many years to develop - anyanalysis that includes trials with less than 10 years of follow-up may not havethe statistical power to show difference in clinical events." To buy Afinitor online is very helpful torestore ones healthy kidneys. The kidneys are organs that serve several essentialregulatory roles in most animals, including vertebrates and some invertebrates.They are essential in the urinary system and also serve homeostatic functionssuch as the regulation of electrolytes, maintenance of acidbase balance, andregulation of blood pressure (via maintaining salt and water balance). Theyserve the body as a natural filter of the blood, and remove wastes which arediverted to the urinary bladder. In producing urine, the kidneys excrete wastessuch as urea and ammonium, and they are also responsible for the reabsorptionof water, glucose, and amino acids. The kidneys also produce hormones includingcalcitriol, erythropoietin, and the enzyme renin. Located at the rear of theabdominal cavity in the retroperitoneum, the kidneys receive blood from thepaired renal arteries, and drain into the paired renal veins. Each kidneyexcretes urine into a ureter, itself a paired structure that empties into theurinary bladder. Renal physiology is the study of kidney function, whilenephrology is the medical specialty concerned with kidney diseases. Diseases ofthe kidney are diverse, but individuals with kidney disease frequently displaycharacteristic clinical features. Common clinical conditions involving thekidney include the nephritic and nephrotic syndromes, renal cysts, acute kidneyinjury, chronic kidney disease, urinary tract infection, nephrolithiasis, andurinary tract obstruction. Various cancers of the kidney exist; the most commonadult renal cancer is renal cell carcinoma. Cancers, cysts, and some otherrenal conditions can be managed with removal of the kidney, or nephrectomy.When renal function, measured by glomerular filtration rate, is persistentlypoor, dialysis and kidney transplantation may be treatment options. Althoughthey are not severely harmful, kidney stones can be a pain and a nuisance. Theremoval of kidney stones includes sound wave treatment to break up the stonesinto smaller pieces, which are then passed through the urinary tract. Onecommon symptom of kidney stones is a sharp pain in the medial/lateral segments ofthe lower back.
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