Docetaxel,induced,allergy,Doce health Docetaxel induced allergy
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Docetaxelsupplier thought that through nursing simple allergy sufferers caused bydocetaxel to find good rash care of patients is very important. Patients, ifshow up allergic skin rashes, medical staff should be prepared to do psychological,skin and diet care, at the same time adjust the body state, enhance the bodyresistance, make patients treating according to the course, to ensure thetreatment effect.A 48-year-old male patient was diagnosed asa right lung papillary adenocarcinoma and alveolar cell carcinoma. The headmulti-enhanced scan intracranial metastases, given the whole brain radiotherapy20 times, meantime line the bisphosphonates treatment of bone metastases. Reviwa month ago found that the intrapulmonary tumors bigger than the previous,given docetaxel single-agent week regimen of three weeks. Chemotherapy regimenof 250 ml of 5% dextrose injection and docetaxel 40 mg, intravenous injection.Patients chemotherapy process is smoothly.Patients on the same day in 9:00 carry on the fourth week docetaxelsingle-agent chemotherapy, at 11:00 the right hand back swelling, mild paingiven chemotherapy extravasation process immediately, namely the partialclosure (10ml saline plus dexamethasone 5mg plus lidocaine 5ml), sustained coldapply. At 4:00pm, the patients hand back swelling disappeared, no pain; nextday, the hand back skin restore normal skin color, private prosecution no localdiscomfort. After one week, the patients hand back suddenly swelling, painextends to the upper limbs, large areas of erythema, given the partial closure immediately,cold apply; next day give dexamethasone 10 mg plus lidocaine 5 ml plusgentamicin 80,000 units plus Yunnanbaiyao 10gmixed into a paste partial to apply, the microwave hyperthermia irradiation for30 minutes. Through four consecutive days of treatment, the patient's symptomsgradually reduced until it disappears, the back of the hand excoriation, localskin more red than normal skin.In this allergy, the skin of patients havelocally severe pain, unbearable, large areas of erythema, three days after showup the exfoliative dermatitis change, thin epidermis easy ulceration. The caremedical personnel should tell patients not scratching the skin, do not use hotwater rinse injured skin; cold apply three times a day, every time 30 minutes;avoid the sun to stimulate the skin. Patient with itching, use saline coldcompresses or with anti-itch cream rubbed; accompanied by blisters, under asepticoperating with a sterile syringe reuse withdrawn the liquid in blister then usebubble film paste bandage, changed 1 times every other day. Give patientshigh-protein diet, high energy, high vitamins, digestible semi-liquid diet,encouraged patients to drink more water, accelerate the excretion of toxicsubstances, eating more green leafy vegetables, fruits, dont eat spicy,seafood, irritating food, dont eat foods with high sugar content, so as not toincrease the sensitization factors, aggravate the symptoms. If feel pain in nighttime,tell patients taking phenol A coffee powder (headache powder) at bedtime, 1packet at a time, so that can ease the pain, and good for sleeping.Source:http://www.cospcn.com
Docetaxel,induced,allergy,Doce